Clinical Evidence
Diabetic Dry
& Itchy Skin
Clinical Study Overview
XTRIMOIST-DM Moisturizing Lotion was clinically evaluated in adults with diabetes
experiencing itchy dry skin.
XTRIMOIST-DM Moisturizing Lotion
Study Duration
45 days
Study Design
Single-group, monocentric clinical study
Key Clinical Findings
Significant Improvement in Skin Hydration
Clinical instrumentation demonstrated a significant increase in skin hydration levels following regular use of XTRIMOIST-DM Moisturizing Lotion.
Clinical Results:
- 43.7% increase in skin hydration within 5 minutes
- 77.5% increase in skin hydration within 1 hour
- 42.2% increase in skin hydration after 45 days
Skin hydration was measured using MoistureMeter SC, a scientific instrument used to evaluate skin moisture levels.
Improved Skin
Barrier Function
XTRIMOIST-DM demonstrated significant reduction in Trans Epidermal Water Loss (TEWL), indicating stronger skin barrier protection and improved moisture retention.
Clinical Results:
- 15.7% reduction in TEWL within 1 hour
- 27.9% reduction in TEWL after 45 days
TEWL measurements were assessed using VapoMeter, a clinically established instrument for evaluating moisture loss from skin.
Clinically Proven Itch
Relief
Participants experienced significant improvement in itching associated with psoriasis.
Clinical Results:
- 100% reduction in itching within 1 hour
- 82.9% reduction in itching after 45 days
Participants also reported noticeable relief from skin discomfort and irritation.
Participant Satisfaction After 45 days of use:
felt hydrated
soft and smooth
had reduced
product overall
Safety & Tolerance
well tolerated throughout the study duration.
Clinical Safety Findings:
- No adverse events reported
- No irritation, burning, tingling, or prickling sensations observed
- No clinically observed skin intolerance reactions
Quality of Life Improvement
- Daily skin comfort
- Emotional well-being related to itching
- Appearance of skin affected by scratching
- Ability to work and enjoy daily activities comfortably
Clinical assessments demonstrated significant improvements in participants’ daily comfort and quality of life.
After 45 days:
- 25.8% of participants reported being “never bothered” by itching that affected their work or enjoyment of life.
- 22.6% of participants reported being “never bothered” by the emotional impact of itching.
Conclusion
- 42.2% increase in skin hydration in 5 min
- 27.9% reduction in TEWL within 1 hour
- 82.9% Moisture retention
- 100% reduction in itching within 1 hour
- Improve in skin softness and smoothness
- Overall skin comfort and quality of life
Clinical evaluation demonstrated that XTRIMOIST-DM Moisturizing Lotion significantly improved multiple skin health parameters. Additionally, the product was well tolerated throughout the 45-day study period.